Mitochondrial Fission and Fusion.

Autor: Patrushev MV; Lomonosov Moscow State University, Faculty of Biology, Moscow, 119991, Russia. piotr.kamenski@gmail.com., Mazunin IO, Vinogradova EN, Kamenski PA
Jazyk: angličtina
Zdroj: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2015 Nov; Vol. 80 (11), pp. 1457-64.
DOI: 10.1134/S0006297915110061
Abstrakt: Mitochondria are key cellular organelles responsible for many different functions. The molecular biology of mitochondria is continuously subject to comprehensive studies. However, detailed mechanisms of mitochondrial biogenesis are still unclear. Fusion and fission are among the most enigmatic processes connected with mitochondria. On the other hand, it has been shown that these events are of great biological importance for functioning of living cells. In this review, we summarize existing molecular data on mitochondrial dynamics and discuss possible biological functions of fusion and fission of these organelles.
Databáze: MEDLINE