Abstrakt: |
The use of the complex system of the biotechnological parameters of cultivation processes permitted the subdivision of the strains belonging to 16 pneumococcal serotypes under study into two groups. The strains characterized by direct relationship between the constructive and energetic parameters of the cultivation process, the faintly pronounced capsule and low virulence are classified with group 1. The characteristic features classified with group 2 were the inverse relationship between the constructive and energetic parameters, intensive capsule formation and higher virulence. The comparative analysis of the strain of serotype 3 and its noncapsular form revealed that the strain showed the loss of virulence and an increase in the energy parameters of the cultivation process. |