Natural antifungal compounds from the peels of Ipomoea batatas Lam.

Autor: Oluyori AP; a Department of Physiscal Science , Landmark University , Omuaran , Nigeria., Shaw AK; b Medicinal and Process Chemistry Division , Central Drug Research Institute , Lucknow , India., Preeti R; b Medicinal and Process Chemistry Division , Central Drug Research Institute , Lucknow , India., Reddy S; b Medicinal and Process Chemistry Division , Central Drug Research Institute , Lucknow , India., Atolani O; c Department of Chemistry , University of Ilorin , Ilorin , Nigeria., Olatunji GA; d Department of Industrial Chemistry , University of Ilorin , Ilorin , Nigeria., Fabiyi OA; e Department of Crop Protection , University of Ilorin , Ilorin , Nigeria.
Jazyk: angličtina
Zdroj: Natural product research [Nat Prod Res] 2016 Sep; Vol. 30 (18), pp. 2125-9. Date of Electronic Publication: 2015 Nov 23.
DOI: 10.1080/14786419.2015.1113413
Abstrakt: Three antifungal compounds have been isolated for the first time from the peels of Ipomoea batatas Lam. Their structures were established on the basis of 1D and 2D NMR spectra data as well as ESI-MS and IR analysis. Urs-13(18)-ene-3β-yl acetate was found to possess a weak activity against Sporothrix schenckii and Trichophyton metagrophytes fungi with an MIC value of 50 μg/mL each. Stigmasterol and 3-friedelanol were equally active against T. metagrophytes.
Databáze: MEDLINE