An update on clinical applications of magnetic nanoparticles for increasing the resolution of magnetic resonance imaging.

Autor: Zeinali Sehrig F; a Young Researchers and Elite Club , Tabriz Branch, Islamic Azad University , Tabriz , Iran.; b Higher Academic Education Institute of Rabe Rashid , Tabriz , Iran., Majidi S; a Young Researchers and Elite Club , Tabriz Branch, Islamic Azad University , Tabriz , Iran.; b Higher Academic Education Institute of Rabe Rashid , Tabriz , Iran., Asvadi S; c Biotechnology Research Center, Sahand University of Technology , Tabriz , Iran., Hsanzadeh A; d Laboratory of Biochemistry, Department of Biology , Faculty of Natural Sciences, University of Tabriz , Tabriz , Iran., Rasta SH; e Medical Bioengineering Department, School of Advanced Medical Sciences , Tabriz University of Medical Sciences , Tabriz , Iran.; f Department of Medical Physics, School of Medicine , Tabriz University of Medical Sciences , Tabriz , Iran.; g Department of Biomedical Physics , School of Medical Sciences, University of Aberdeen , Aberdeen , UK., Emamverdy M; h Department of Chemistry Engineering , Ahar Branch, Islamic Azad University , Ahar , Iran., Akbarzadeh J; c Biotechnology Research Center, Sahand University of Technology , Tabriz , Iran., Jahangiri S; h Department of Chemistry Engineering , Ahar Branch, Islamic Azad University , Ahar , Iran., Farahkhiz S; h Department of Chemistry Engineering , Ahar Branch, Islamic Azad University , Ahar , Iran., Akbarzadeh A; i Biotechnology Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.; j Department of Medical Nanotechnologies , Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences , Tabriz , Iran.
Jazyk: angličtina
Zdroj: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2016 Nov; Vol. 44 (7), pp. 1583-8. Date of Electronic Publication: 2015 Nov 19.
DOI: 10.3109/21691401.2015.1101001
Abstrakt: Today, technologies based on magnetic nanoparticles (MNPs) are regularly applied to biological systems with diagnostic or therapeutic aims. Nanoparticles made of the elements iron (Fe), gadolinium (Gd) or manganese (Mn) are generally used in many diagnostic applications performed under magnetic resonance imaging (MRI). Similar to molecular-based contrast agents, nanoparticles can be used to increase the resolution of imaging while offering well biocompatibility, poisonousness and biodistribution. Application of MNPs enhanced MRI sensitivity due to the accumulation of iron in the liver caused by discriminating action of the hepatobiliary system. The aim of this study is about the use, properties and advantages of MNPs in MRI.
Databáze: MEDLINE
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