Immunomodulation and Disease Tolerance to Staphylococcus aureus.

Autor:	Li Z; Microbiome and Disease Tolerance Center, Department of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada. zhigang.li@mail.mcgill.ca., Peres AG; Microbiome and Disease Tolerance Center, Department of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada. adam.peres@mail.mcgill.ca., Damian AC; Microbiome and Disease Tolerance Center, Department of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada. andreea.damian@mail.mcgill.ca., Madrenas J; Microbiome and Disease Tolerance Center, Department of Microbiology and Immunology, McGill University, Montréal, QC, H3A 2B4, Canada. joaquin.madrenas@mcgill.ca.
Jazyk:	angličtina
Zdroj:	Pathogens (Basel, Switzerland) [Pathogens] 2015 Nov 13; Vol. 4 (4), pp. 793-815. Date of Electronic Publication: 2015 Nov 13.
DOI:	10.3390/pathogens4040793
Abstrakt:	The Gram-positive bacterium Staphylococcus aureus is one of the most frequent pathogens that causes severe morbidity and mortality throughout the world. S. aureus can infect skin and soft tissues or become invasive leading to diseases such as pneumonia, endocarditis, sepsis or toxic shock syndrome. In contrast, S. aureus is also a common commensal microbe and is often part of the human nasal microbiome without causing any apparent disease. In this review, we explore the immunomodulation and disease tolerance mechanisms that promote commensalism to S. aureus.
Databáze:	MEDLINE
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