[Application of Reporter Gene Labeling in Stem Cell Therapy for Acute Myocardial Infarction].

Autor: Li X; Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China., Jin ZY; Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China., Wang YN; Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
Jazyk: čínština
Zdroj: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae [Zhongguo Yi Xue Ke Xue Yuan Xue Bao] 2015 Oct; Vol. 37 (5), pp. 612-7.
DOI: 10.3881/j.issn.1000-503X.2015.05.021
Abstrakt: Stem cell therapy for acute myocardial infarction is drawing great attention. However,the biological behavior and function mechanism of implanted stem cells remain controversial, as well as their clinical benefits. With the development of imaging probes and devices, molecular imaging enables noninvasive, dynamic tracking of stem cells in vivo. In this review, we summarize the use of various markers,especially the technique of reporter gene labeling, in the field of stem cell therapy, and highlight some recent preclinical and clinical achievements.
Databáze: MEDLINE