HemaSpot, a Novel Blood Storage Device for HIV-1 Drug Resistance Testing.

Autor:	Brooks K; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA., DeLong A; Center for Statistical Sciences, School of Public Health, Brown University, Providence, Rhode Island, USA., Balamane M; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA., Schreier L; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA., Orido M; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya., Chepkenja M; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya., Kemboi E; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya., D'Antuono M; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA., Chan PA; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA., Emonyi W; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya., Diero L; Academic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya Department of Medicine, School of Medicine, College of Health Sciences, Moi University, Eldoret, Kenya., Coetzer M; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA., Kantor R; Division of Infectious Diseases, Alpert Medical School, Brown University, Providence, Rhode Island, USA rkantor@brown.edu.
Jazyk:	angličtina
Zdroj:	Journal of clinical microbiology [J Clin Microbiol] 2016 Jan; Vol. 54 (1), pp. 223-5. Date of Electronic Publication: 2015 Nov 11.
DOI:	10.1128/JCM.02853-15
Abstrakt:	HemaSpot, a novel dried-blood storage filter device, was used for HIV-1 pol resistance testing in 30 fresh United States blood samples and 54 previously frozen Kenyan blood samples. Genotyping succeeded in 79% and 58% of samples, respectively, improved with shorter storage and higher viral load, and had good (86%) resistance mutation concordance to plasma. (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
Databáze:	MEDLINE
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