99mTc-HYNIC-TOC increased uptake can mimic malignancy in the pancreas uncinate process at somatostatin receptor SPECT/CT.

Autor: Yamaga LY; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil. itayay@hotmail.com., Neto GC; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., da Cunha ML; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., Osawa A; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., Oliveira JC; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., Fonseca RQ; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., Nogueira SA; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., Wagner J; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil., Funari MG; Imaging Department, Albert Einstein Hospital, Av. Albert Einstein, 627, São Paulo, CEP: 05651-090, Brazil.
Jazyk: angličtina
Zdroj: La Radiologia medica [Radiol Med] 2016 Mar; Vol. 121 (3), pp. 225-8. Date of Electronic Publication: 2015 Nov 12.
DOI: 10.1007/s11547-015-0593-2
Abstrakt: Objective: The aim of this study was to assess the occurrence and frequency of increased physiologic uptake of 99mTc-HYNIC-TOC by the uncinate process of the pancreas in SPECT/CT images.
Methods: Forty-six scans of 41 patients were evaluated retrospectively. The uptake of 99mTc-HYNIC-TOC was considered to be physiologic in patients with normal findings at dedicated abdominal CT or MR and lack of neoplastic lesions in clinical follow-ups. The intensity of uncinate process uptake was compared to the uptake of the normal liver.
Results: Focal uptake was attributed to the presence of pancreatic NET in 5 patients. Among the 36 patients without any evidence of malignancy in CT, MR and follow-up, 7 (19.4 %) showed increased uptake in the uncinate process. The intensity of uptake was lesser in 3 (8.3 %), similar in 3 and greater than the normal liver in 1 (2.8 %) case.
Conclusion: Increased 99mTc-HYNIC-TOC uptake occurred in 19.4 % of those subjects without any evidence of neuroendocrine tumor in the uncinate process.
Databáze: MEDLINE
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