| Autor: |
Rajput CS; Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Meerut 250002, India ; Jubilant Chemsys Ltd. R & D B-34, Sector 58, Noida 201301, India., Singhal S; Medicinal Chemistry Division, Department of Pharmacology, L.L.R.M. Medical College, Meerut 250002, India. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of pharmaceutics [J Pharm (Cairo)] 2013; Vol. 2013, pp. 907525. Date of Electronic Publication: 2013 Jan 17. |
| DOI: |
10.1155/2013/907525 |
| Abstrakt: |
A series of 3-[2'-(Substitutedbenzylideneamino)phenyl]-2-methyl-6-substituted quinazolin-4-ones (5-10), 3-[2'-(3(″)-chloro-2(″)-oxo-4(″)-substitutedphenylazetidin-1(″)-yl)phenyl]-2-methyl-6-substitutedquinazolin-4-ones (11-16), and 3-[2'-(2(″)-substitutedphenyl-4(″)-oxo-1(″),3(″)-thiazolidin-3(″)-yl)phentl]-2-methyl-6-substitutedquinazolin-4-ones (17-22) have been synthesized in the present study. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, (1)H NMR, and mass spectral data. All the newly synthesized compounds were screened for anti-inflammatory and analgesic activities. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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