| Autor: |
Ivanov AA, Bulynina TM, Molokanov AG, Vorozhtsova SV, Utina DM, Severyukhin YS, Ushakov IB |
| Jazyk: |
ruština |
| Zdroj: |
Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine [Aviakosm Ekolog Med] 2015; Vol. 49 (4), pp. 26-30. |
| Abstrakt: |
The experiments were performed with outbred CD-1 male mice (SPF category). Total irradiation at 1.0; 2.5 and 5.0 Gy by protons with the average energy of 170 MeV was conducted in a level medical beam of the phasotron at the Joint Institute of Nuclear Investigations. Targets were 2 points of in-depth dose distribution, i.e. beam entrance of the object, and modified Bragg peak. As a physical protector, the comb filter increases linear energy transfer (LET) of 170 MeV entrance protons from 0.49 keV/μm to 1.6 keV/μm and, according to the bone marrow test, doubles the biological effectiveness of protons when comparing radiation doses that cause 37% inhibition of blood cell formation in the bone marrow. Physical protection increases dose rate from 0.37 Gy/min for entrance protons to 0.8 Gy/min for moderated protons which more than in thrice reduces time of irradiation needed to reach an equal radiobiological effect. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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