[Influence of gravity discharge on the content of isatin-binding proteins in mice: results of ground-based and space research under the program Bion-M №1].

Autor:	Ivanov AS; Institute of Biomedical Chemistry, Moscow, Russia., Medvedev AE; Institute of Biomedical Chemistry, Moscow, Russia., Buneeva OA; Institute of Biomedical Chemistry, Moscow, Russia., Gnedenko OV; Institute of Biomedical Chemistry, Moscow, Russia., Ershov PV; Institute of Biomedical Chemistry, Moscow, Russia., Mezencev YV; Institute of Biomedical Chemistry, Moscow, Russia., Yablokov EO; Institute of Biomedical Chemistry, Moscow, Russia., Kaluzhsky LA; Institute of Biomedical Chemistry, Moscow, Russia., Florinskaya AV; Institute of Biomedical Chemistry, Moscow, Russia., Moskaleva NE; Institute of Biomedical Chemistry, Moscow, Russia., Zgoda VG; Institute of Biomedical Chemistry, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Biomeditsinskaia khimiia [Biomed Khim] 2015 Sep-Oct; Vol. 61 (5), pp. 632-5.
DOI:	10.18097/PBMC20156105632
Abstrakt:	Isatin-binding activity of mice liver proteins has been investigated in the samples from the control and flight groups by using the methods of biosensor and proteomic analysis. It was found the higher isatin-binding activity in mice of flight group. The content of a number of individual isatin-binding proteins in the samples of the flight groups differ slightly from the ground control. However, in samples from animals which have weekly post-flight adaptation, the level of certain proteins was significantly increased. The latter allows us to assume that the main events in the proteome of mice (at least in subproteome of isatin-binding proteins), occurs in early post-flight period.
Databáze:	MEDLINE
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