Advances in high-density lipoprotein physiology: surprises, overturns, and promises.

Autor:	Constantinou C; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Karavia EA; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Xepapadaki E; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Petropoulou PI; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Papakosta E; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Karavyraki M; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Zvintzou E; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Theodoropoulos V; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Filou S; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Hatziri A; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Kalogeropoulou C; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Panayiotakopoulos G; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece., Kypreos KE; Pharmacology Department, University of Patras Medical School, Rio Achaias, Greece kkypreos@med.upatras.gr.
Jazyk:	angličtina
Zdroj:	American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2016 Jan 01; Vol. 310 (1), pp. E1-E14. Date of Electronic Publication: 2015 Nov 03.
DOI:	10.1152/ajpendo.00429.2015
Abstrakt:	Emerging evidence strongly supports that changes in the HDL metabolic pathway, which result in changes in HDL proteome and function, appear to have a causative impact on a number of metabolic disorders. Here, we provide a critical review of the most recent and novel findings correlating HDL properties and functionality with various pathophysiological processes and disease states, such as obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, inflammation and sepsis, bone and obstructive pulmonary diseases, and brain disorders. (Copyright © 2016 the American Physiological Society.)
Databáze:	MEDLINE
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