Synaptosome-associated protein 25 (SNAP25) synthesis in terminal buttons of mouse motor neuron.

Autor: Islamov RR; Kazan State Medical University, ul. Butlerova 49, Kazan, 420012, Tatarstan, Russia., Samigullin DV; Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, ul. Lobachevskogo 2/31, Kazan, 420111, Russia. samid75@mail.ru.; Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia. samid75@mail.ru., Rizvanov AA; Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia., Bondarenko NI; Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia., Nikolskiy EE; Kazan State Medical University, ul. Butlerova 49, Kazan, 420012, Tatarstan, Russia.; Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, ul. Lobachevskogo 2/31, Kazan, 420111, Russia.; Kazan (Volga Region) Federal University, ul. Kremlevskaya 18, Kazan, 420008, Tatarstan, Russia.
Jazyk: angličtina
Zdroj: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2015; Vol. 464, pp. 272-4. Date of Electronic Publication: 2015 Oct 31.
DOI: 10.1134/S1607672915050026
Abstrakt: Previously, we formulated the hypothesis of compartmentalized protein synthesis in axons of motor neurons. In the axon hillock, along the entire length of the axon and in its ending, specific proteins are locally synthesized, which ensure the function of each compartment. In support of this hypothesis, in this work we studied the local protein synthesis in mouse motor nerve ending.
Databáze: MEDLINE