Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil.

Autor:	Almeida TN; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Fiaccadori FS; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Souza M; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Borges AM; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil., Cardoso Dd; Departamento de Microbiologia, Imunologia, Parasitologia e Patologia Geral, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
Jazyk:	angličtina
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2015 Sep-Oct; Vol. 48 (5), pp. 599-602.
DOI:	10.1590/0037-8682-0023-2015
Abstrakt:	Introduction: In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before and after RVA vaccine-introduction in Brazil. Methods: Eighty samples were screened for the presence of RVA. Positive samples were molecularly analyzed. Results: RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination: predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and IIc (G2) lineages and I2 and E2 genotypes. Conclusions: Although changes in RVA-circulation pattern were observed in the post-vaccination period, it could not be attributed to vaccination process.
Databáze:	MEDLINE
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