Renal function assessment in atrial fibrillation: Usefulness of chronic kidney disease epidemiology collaboration vs re-expressed 4 variable modification of diet in renal disease.

Autor:	Abumuaileq RR; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., Abu-Assi E; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., López-López A; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., Raposeiras-Roubin S; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., Rodríguez-Mañero M; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., Martínez-Sande L; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., García-Seara FJ; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., Fernandez-López XA; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain., González-Juanatey JR; Rami Riziq-Yousef Abumuaileq, Emad Abu-Assi, Andrea López-López, Sergio Raposeiras-Roubin, Moisés Rodríguez-Mañero, Luis Martínez-Sande, Francisco Javier García-Seara, Xesus Alberte Fernandez-López, Jose Ramón González-Juanatey, Cardiology Department, University Clinical Hospital of Santiago de Compostela, 15706 Santiago de Compostela, Spain.
Jazyk:	angličtina
Zdroj:	World journal of cardiology [World J Cardiol] 2015 Oct 26; Vol. 7 (10), pp. 685-94.
DOI:	10.4330/wjc.v7.i10.685
Abstrakt:	Aim: To compare the performance of the re-expressed Modification of Diet in Renal Disease equation vs the new Chronic Kidney Disease Epidemiology Collaboration equation in patients with non-valvular atrial fibrillation. Methods: We studied 911 consecutive patients with non-valvular atrial fibrillation on vitamin-K antagonist. The performance of the re-expressed Modification of Diet in Renal Disease equation vs the new Chronic Kidney Disease Epidemiology Collaboration equation in patients with non-valvular atrial fibrillation with respect to either a composite endpoint of major bleeding, thromboembolic events and all-cause mortality or each individual component of the composite endpoint was assessed using continuous and categorical ≥ 60, 59-30, and < 30 mL/min per 1.73 m(2) estimated glomerular filtration rate. Results: During 10 ± 3 mo, the composite endpoint occurred in 98 (10.8%) patients: 30 patients developed major bleeding, 18 had thromboembolic events, and 60 died. The new equation provided lower prevalence of renal dysfunction < 60 mL/min per 1.73 m(2) (32.9%), compared with the re-expressed equation (34.1%). Estimated glomerular filtration rate from both equations was independent predictor of composite endpoint (HR = 0.98 and 0.97 for the re-expressed and the new equation, respectively; P < 0.0001) and all-cause mortality (HR = 0.98 for both equations, P < 0.01). Strong association with thromboembolic events was observed only when estimated glomerular filtration rate was < 30 mL/min per 1.73 m(2): HR is 5.1 for the re-expressed equation, and HR = 5.0 for the new equation. No significant association with major bleeding was observed for both equations. Conclusion: The new equation reduced the prevalence of renal dysfunction. Both equations performed similarly in predicting major adverse outcomes.
Databáze:	MEDLINE
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