[Research progress of TRPV4 and cerebral ischemic reperfusion injury].

Autor: Ding H; Class 4 Grade 2012, Seven-year Program of Clinical Medicine, Nanjing Medical University, Nanjing 210029, China., Lin YX; Class 4 Grade 2012, Seven-year Program of Clinical Medicine, Nanjing Medical University, Nanjing 210029, China., Shen QW; Class 4 Grade 2012, Seven-year Program of Clinical Medicine, Nanjing Medical University, Nanjing 210029, China., Pan Z; Class 4 Grade 2012, Seven-year Program of Clinical Medicine, Nanjing Medical University, Nanjing 210029, China., Wang ZC; Class 4 Grade 2012, Seven-year Program of Clinical Medicine, Nanjing Medical University, Nanjing 210029, China., Chen L; Department of Physiology, Nanjing Medical University, Nanjing 210029, China. chenl@njmu.edu.cn.
Jazyk: čínština
Zdroj: Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2015 Oct 25; Vol. 67 (5), pp. 527-32.
Abstrakt: Transient receptor potential vanilloid 4 (TRPV4) channel is a member of transient receptor potential superfamily. TRPV4 is selectively permeable to calcium. Activation of the TRPV4 channel induces an increase in intracellular calcium concentration and plays an important role under physiological and pathological conditions. Especially, there is evidence showing that TRPV4 is involved in cerebral ischemic reperfusion injury. The present paper reviewed some research progress about the role of TRPV4 in cerebral ischemic reperfusion injury.
Databáze: MEDLINE