Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern.

Autor: Matigian N; Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, 4072, Australia ; Eskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia., Brooke G; Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia., Zaibak F; Murdoch Children's Research Institute, The University of Melbourne, Royal Children's Hospital, Parkville, Victoria, 3052, Australia., Rossetti T; Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia., Kollar K; Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia., Pelekanos R; Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia., Heazlewood C; Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia., Mackay-Sim A; Eskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia., Wells CA; Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, 4072, Australia ; Eskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia ; The Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, The University of Glasgow, Scotland, G12 8TA, UK., Atkinson K; Mater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
Jazyk: angličtina
Zdroj: Genomics data [Genom Data] 2014 Nov 28; Vol. 3, pp. 70-4. Date of Electronic Publication: 2014 Nov 28 (Print Publication: 2015).
DOI: 10.1016/j.gdata.2014.11.011
Abstrakt: Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic stem cells (USSCs), human placental-derived mesenchymal stem cells (hpMSCs), and human bone marrow-derived mesenchymal stromal cells (bmMSCs), all derived from four different donors. The microarray data are available on the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number E-TABM-880. Additionally, the data has been integrated into a public portal, www.stemformatics.org. Our data provide a resource for understanding the differences in MSCs derived from different tissues.
Databáze: MEDLINE