[Prevalence of vitamin D deficiency in children aged 5-10 years in western Brittany].

Autor: Beuzit C; Service de pédiatrie et génétique médicale, CHRU de Brest, 2, avenue Foch, 29200 Brest, France., L'Hour MC; Service de pédiatrie et génétique médicale, CHRU de Brest, 2, avenue Foch, 29200 Brest, France., Roudaut S; Centre d'investigation clinique, CHRU de Brest, 29200 Brest, France., Gouillou M; Centre d'investigation clinique, CHRU de Brest, 29200 Brest, France., Metz C; Service de pédiatrie et génétique médicale, CHRU de Brest, 2, avenue Foch, 29200 Brest, France., Moineau MP; Département de biochimie et pharmacologie-toxicologie, CHRU de Brest, 29200 Brest, France., Kerspern H; Département de biochimie et pharmacologie-toxicologie, CHRU de Brest, 29200 Brest, France., de Parscau L; Service de pédiatrie et génétique médicale, CHRU de Brest, 2, avenue Foch, 29200 Brest, France., Teissier R; Service de pédiatrie et génétique médicale, CHRU de Brest, 2, avenue Foch, 29200 Brest, France. Electronic address: raphael.teissier@chu-brest.fr.
Jazyk: francouzština
Zdroj: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [Arch Pediatr] 2015 Nov; Vol. 22 (11), pp. 1112-8. Date of Electronic Publication: 2015 Oct 09.
DOI: 10.1016/j.arcped.2015.08.013
Abstrakt: Unlabelled: French guidelines do not recommend systematic supplementation of vitamin D in children aged 5-10 years old owing to the lack of data on vitamin D status in this age group. Our objective was to assess the prevalence of vitamin D deficiency in these children.
Methodology: Single-center, prospective, epidemiological study including 358 children aged 0-15 years. The endpoint was the concentration of vitamin D.
Results: In all, 316 children were divided into four groups according to age: 0-18 months (n=113); 18 months to 5 years (n=103); 5-10 years (n=62); and 10-15 years (n=38). The median concentration of vitamin D decreased with age (P<0.001): 90.2 nmol/L in the group aged 0-18 months; 56.7 nmol/L in the group aged 18 months to 5 years; 49.05 nmol/L in the group aged 5-10 years; and 42.45 nmol/L in the group aged 10-15 years. This corresponds to an increase in the prevalence of vitamin D deficiency in children aged 5-10 years (51.6% vs. 8.8% in the group aged 0-18 months, P<0.001). For children aged 5-10 years, the prevalence of deficiency was greater in the non-supplementation group (75%) compared with the supplementation group (13%; P<0.001).
Conclusion: This study demonstrates the high prevalence of vitamin D deficiency in children aged 5-10 years and the relationship between supplementation and vitamin D status. It provides an argument in favor of supplementation in children aged 5-10 years in this region and a reconsideration of the French recommendations.
(Copyright © 2015 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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