[The relationship between platelet count and mean platelet volume with obstructive sleep apnea syndrome].

Autor: Atan D; Department of Otolaryngology, Ankara Numune Training and Research Hospital, 06100 Altındağ, Ankara, Turkey. doganatan@gmail.com., Sazak Kundi FC, Özcan KM, Dere H
Jazyk: turečtina
Zdroj: Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat [Kulak Burun Bogaz Ihtis Derg] 2015; Vol. 25 (5), pp. 289-94.
DOI: 10.5606/kbbihtisas.2015.47427
Abstrakt: Objectives: This study aims to investigate the relationship between platelet count and mean platelet volume (MPV) with obstructive sleep apnea syndrome (OSAS).
Patients and Methods: This retrospective study included 417 OSAS patients (284 males, 133 females; mean age 47.9±10.0; range 23 to 75 years) who were performed polisomnography (PSG) in our clinic between January 2013 and December 2014. Patients were divided into two groups according to apnea-hipopnea index (AHI). Apnea-hipopnea index <5 was assumed as normal, while AHI ≥5 was assumed as OSAS. Platelet count and MPV values of group with normal AHI and group with OSAS were statistically compared. Apnea-hipopnea index, REM AHI, non-REM AHI, minimum oxygen saturation, and duration of oxygen saturation remaining below 90% were statistically compared with platelet count and MPV.
Results: The mean of platelet count in non-OSAS and OSAS groups were 262.31±65.78 and 252.77±61.86, respectively, with no statistically significant difference between the groups. Mean platelet volume in non-OSAS and OSAS groups were 9.56±1.88 and 9.71±1.57, respectively; however, the difference was not statistically significant. Platelet count increased statistically significantly as AHI, REM AHI, non-REM AHI, and minimum oxygen saturation parameters got impaired.
Conclusion: As PSG parameters get impaired, platelet count increases in OSAS patients.
Databáze: MEDLINE