Clinical experience with ciprofloxacin: analysis of a multicenter study.

Autor: Simmons JF, Cowley CE, Dozier DB, Galdini AM, Manes MR, Nungester GH, Schreeder MT, Strother KD, Chun BW
Jazyk: angličtina
Zdroj: Alabama medicine : journal of the Medical Association of the State of Alabama [Ala Med] 1989 Feb; Vol. 58 (8), pp. 10-3.
Abstrakt: In a multicenter study of 128 patients treated with ciprofloxacin (mean daily dosage, 982 mg per day; mean duration of treatment, 8.9 days) for a variety of infections, 48 were microbiologically proven. Of these, bacteriologic cure and/or improvement resulted in 93% of cases. For all 128 infections clinical cure and/or improvement resulted in 93.8% of cases. Twenty-nine (23.8%) of all infections were classified as chronic. Overall, there were 3/128 (2.3%) adverse reactions (ADRs); one case each of diarrhea, malaise, and nausea/vomiting. None were related definitely to ciprofloxacin therapy. Therapy with ciprofloxacin was discontinued in two (1.6%) of 128 patients because of adverse gastrointestinal (GI) effects. One patient elected to continue ciprofloxacin therapy despite mild GI side effects.
Databáze: MEDLINE