Evaluation of ophthalmic and hemodynamic parameters in capuchin monkeys (Sapajus sp.) submitted to dissociative anesthetic protocols.

Autor: Raposo AC; School of Veterinary Medicine and Zootechny, Federal University of Bahia UFBA, Salvador, BA, Brazil., Ofri R; The Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel., Schaffer DP; School of Veterinary Medicine and Zootechny, Federal University of Bahia UFBA, Salvador, BA, Brazil., Gomes Júnior DC; School of Veterinary Medicine and Zootechny, Federal University of Bahia UFBA, Salvador, BA, Brazil., Libório FA; Screening Center for Wild Animals (CETAS), Salvador, BA, Brazil., Martins Filho EF; Faculdade de Ciências Agrárias e Veterinárias, UNESP, São Paulo State University, Jaboticabal, SP, Brazil., Oriá AP; School of Veterinary Medicine and Zootechny, Federal University of Bahia UFBA, Salvador, BA, Brazil.
Jazyk: angličtina
Zdroj: Journal of medical primatology [J Med Primatol] 2015 Dec; Vol. 44 (6), pp. 381-9. Date of Electronic Publication: 2015 Oct 12.
DOI: 10.1111/jmp.12200
Abstrakt: Background: Dissociative drugs are used for chemical restraint in monkeys. The aim was to evaluate muscle relaxation, recovery, and ophthalmic and hemodynamic parameters in 24 capuchin monkeys subjected to four dissociative anesthesia protocols.
Methods: Animals were anesthetized with tiletamine-zolazepam (TZ), ketamine-xylazine (KX), ketamine-midazolam (KM), or ketamine-dexmedetomidine (KD). Muscle relaxation, digital reflex, lacrimal production, intraocular pressure (IOP), heart and respiratory rates, oxygen saturation (SpO2 ), rectal temperature, non-invasive arterial blood pressure, palpebral and pupillary reflexes, and eyeball positioning were evaluated every 5 minutes for 20 minutes.
Results: Muscle relaxation was highest in KM and KD. At 5-minute post-injection, IOP was higher in TZ than in all other groups. There was a significant difference between groups and times in heart and respiratory rates and temperature. There were no significant differences in SpO2, arterial blood pressure, and lacrimal production between groups.
Conclusions: The established parameters may help in clinical and ophthalmic examinations of primates.
(© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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