[Effectiveness and safety of antiviral therapy of military personnel suffering from chronic hepatitis C].

Autor: Zhdanov KV, Gusev DA, Kozlov KV, Shishkin MK, Sukachev VS, Shakhmanov DM, Zhabrov SS
Jazyk: ruština
Zdroj: Voenno-meditsinskii zhurnal [Voen Med Zh] 2015 Apr; Vol. 336 (4), pp. 44-9.
Abstrakt: In order to evaluate effectiveness and safety of antiviral therapy schemes examined and treated 191 patients with chronic bepatitis C were assigned standard interferon and ribavirin, pegslated interferon and ribavirin, the total duration of the course coput 24-48 weeks. Based on clinical and laboratory parameters evaluated the safety of antiviral therapy. Formation of sustainable viral response, depending on the genotype observed, was given at 58,9-70%.of patients. In case of insufficient. antiviral therapy was prescribed a second course that will improve the effectiveness of treatment to 90-95%. Correction of adverse events was held lower dosages of interferon and/or ribavirin.
Databáze: MEDLINE