Impact of Regional Vein Thrombosis in Patients with Klebsiella pneumoniae Liver Abscess.
| Autor: | Molton JS; University Medicine Cluster, National University Health System, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chee YL; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Hematology-Oncology, National University Health System, Singapore., Hennedige TP; Department of Diagnostic Imaging, National University Health System, Singapore., Venkatesh SK; Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America., Archuleta S; University Medicine Cluster, National University Health System, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | PloS one [PLoS One] 2015 Oct 07; Vol. 10 (10), pp. e0140129. Date of Electronic Publication: 2015 Oct 07 (Print Publication: 2015). |
| DOI: | 10.1371/journal.pone.0140129 |
| Abstrakt: | Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|