Temperature measurement in human fat with T2 imaging.

Autor: Parmala M; Philips Medical Systems MR Finland, Vantaa, Finland., Eriksson M; Philips Medical Systems MR Finland, Vantaa, Finland., Rytioja M; Philips Medical Systems MR Finland, Vantaa, Finland., Tanttu J; Philips Medical Systems MR Finland, Vantaa, Finland., Köhler M; Philips Medical Systems MR Finland, Vantaa, Finland.
Jazyk: angličtina
Zdroj: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2016 May; Vol. 43 (5), pp. 1171-8. Date of Electronic Publication: 2015 Oct 05.
DOI: 10.1002/jmri.25064
Abstrakt: Purpose: To develop a method for noninvasive T2 -based thermometry that enables estimation of the in vivo temperature in adipose tissues at both 1.5T and 3T field strengths.
Materials and Methods: A total of 27 apparent T2 -temperature measurement sets were performed on 13 human abdominal adipose tissue samples using an inversion prepared dual-echo single-slice sequence for apparent T2 estimation. The measurements were performed on Ingenia 1.5T and 3.0T scanners and Achieva 1.5T and 3.0T scanners. The apparent T2 -values were measured at 4°C temperature intervals during heating from 21 to 45°C and cooling to 21°C. A two-parameter exponential fit was used to estimate the apparent T2 to temperature dependency on a scanner-to-scanner basis.
Results: In the temperature range evaluated (21-45°C), the apparent T2 relaxation times increased from an average of ∼100 msec to 190 msec at 1.5T and an average of ∼130 msec to 220 msec at 3T. The measured T2 -relaxation times followed the calibration curve with a median absolute error of 0.37°C and maximum error of 1.7°C in 12 of the 13 samples, with the outlier having a notably different appearance upon visual inspection prior to measurement.
Conclusion: Changes in apparent T2 relaxation time has the potential to be used for accurately estimating local temperature within in vivo subcutaneous fat.
(© 2015 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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