| Autor: |
Koa EY; Jeju Center, Korea Basic Science Institute (KBSI), Jeju 690-140, Republic of Korea ; Department of Marine Life Science, Jeju National University, Jeju 690-756, Republic of Korea., Kim D; Jeju Center, Korea Basic Science Institute (KBSI), Jeju 690-140, Republic of Korea., Roh SW; Jeju Center, Korea Basic Science Institute (KBSI), Jeju 690-140, Republic of Korea., Yoonc WJ; Jeju Biodiversity Research Institute, Jeju Technopark, Jeju, 699-943, Republic of Korea., Jeon YJ; Department of Marine Life Science, Jeju National University, Jeju 690-756, Republic of Korea., Ahn G; Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu 550-749, Republic of Korea., Kim KN; Jeju Center, Korea Basic Science Institute (KBSI), Jeju 690-140, Republic of Korea. |
| Abstrakt: |
In this study, the antioxidant properties of 80 % ethanol extracts of 16 species of plants from Jeju Island in Korea were evaluated using various antioxidant assays, including the DPPH (1,1-Diphenyl-2-pricrylhydrazyl) radical scavenging, superoxide scavenging, xanthine oxidase inhibition and hydrogen peroxide scavenging activities. Among the 16 plant extracts tested, CN-13 showed strong antioxidant properties in the DPPH radical scavenging and hydrogen peroxide scavenging tests. The CN-13 ethanol extract was thus selected to be used for further experiments, and was separated into various fractions using four different organic solvents (n-hexane, methylene chloride, ethyl acetate and butanol). The ethyl acetate fraction of CN-13 extract evidenced strong DPPH radical scavenging properties as compared to the other fractions. The ethyl acetate fraction also strongly inhibited DNA-damage induced by hydrogen peroxide-oxidative damage in a mouse lymphoma (L5178Y-R) cell line. Moreover, a correlation between the total phenolic content of the extract, and its antioxidant property was reported. |
