Pythium insidiosum: A Rare Necrotizing Orbital and Facial Infection.
| Autor: | Kirzhner M; Department of Ophthalmology, University of Tennessee Health Science Center, Hamilton Eye Institute, Memphis;, Arnold SR; Department of Pediatrics, Division of Infectious Diseases, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis;, Lyle C; Department of Ophthalmology, University of Tennessee Health Science Center, Hamilton Eye Institute, Memphis;, Mendoza LL; Biomedical Laboratory Diagnostics, Microbiology and Molecular Genetics, Michigan State University, East Lansing., Fleming JC; Department of Ophthalmology, University of Tennessee Health Science Center, Hamilton Eye Institute, Memphis; |
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| Jazyk: | angličtina |
| Zdroj: | Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2015 Mar; Vol. 4 (1), pp. e10-3. Date of Electronic Publication: 2014 Mar 24. |
| DOI: | 10.1093/jpids/piu015 |
| Abstrakt: | Pythium insidiosum, also known as "swamp cancer," has been long known for its destructive effects on plants and animals. Infections with this fungus-like organism typically occur in temperate, tropical, and subtropical regions [ 1]. Human infection with P insidiosum, although exceedingly rare, is characterized by invasion of the cornea, cutaneous, subcutaneous, and orbital tissues with eosinophilic, tumor-like masses demonstrating arterial tropism [ 1, 2]. In most cases, patients have a history of recent exposure to wet environments [ 1]. If left untreated, P insidiosum is fatal, because it is an angioinvasive organism that leads to thrombosis and tissue ischemia. Reports of most human cases are from Thailand, with only 4 well documented orbital cases to date in the United States and Australia [ 1, 3, 4]. (© The Author 2014. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.) |
| Databáze: | MEDLINE |
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