[Clinical and biochemical characteristics in patients with histology compatible with steatothepatitis in National Hospital Arzobispo Loayza, Lima, Peru, from 2010 to 2012].

Autor: Alegría Matos PH; Facultad de Medicina Alberto Hurtado. Universidad Peruana Cayetano Heredia. Lima, PerÚ., Tafur Cabello KS; Facultad de Medicina Alberto Hurtado. Universidad Peruana Cayetano Heredia. Lima, PerÚ., Lozano Miranda A; Departamento de GastroenterologÍa. Hospital Nacional Arzobispo Loayza. Lima, PerÚ., Loza Munarriz C; Departamento de NefrologÍa. Hospital Nacional Cayetano Heredia. Lima, PerÚ., Lozano Miranda Z; Departamento de PatologÍa. Hospital Nacional Arzobispo Loayza. Lima, PerÚ.
Jazyk: Spanish; Castilian
Zdroj: Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru [Rev Gastroenterol Peru] 2015 Jul-Sep; Vol. 35 (3), pp. 236-42.
Abstrakt: Objectives: Describe the clinical and biochemical characteristics of patients with histopathological findings compatible with steatohepatitis of HNAL patients between 2010-2012. Determine the frequency of alcoholic and non-alcoholic steatohepatitis, presence of metabolic syndrome and other factors associated to non-alcoholic steatohepatitis, its main indications for liver biopsy and biochemical characteristics according to the severity of the histological findings.
Materials and Methods: We evaluated all histological slides of liver biopsies of the period between 2010-2012, of which, those with the diagnosis of steatohepatitis were selected. Their medical records were then reviewed.
Results: 32 patients met inclusion criteria. 28 were female and 4 male, the average age was 49±12 years. Two patients had a history of chronic alcohol consumption, representing the group of alcoholic steatohepatitis. The more frequent clinical finding in patients with NASH (non-alcoholic steatohepatitis), was obesity (37%). 50% of patients had AST/ALT ratio <1.
Conclusions: Among population studied, non-alcoholic steatohepatitis was more common than alcoholic steatohepatitis, being obesity the most associated factor.
Databáze: MEDLINE