Detection of Antibodies In Vitro Binding to Endothelial Cells in the Sera from Women with Normal Pregnancy and Preeclampsia.

Autor: Ziganshina MM; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia. mmz@mail.ru.; D. O. Ott Research Institute of Obstetrics and Gynecology, North Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia. mmz@mail.ru., Nikolaeva MA; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia., Stepanova EO; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia., Krechetova LV; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia., Kan NE; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia., Sokolov DI; D. O. Ott Research Institute of Obstetrics and Gynecology, North Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia., Sel'kov SA; D. O. Ott Research Institute of Obstetrics and Gynecology, North Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia., Sukhikh GT; V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2015 Aug; Vol. 159 (4), pp. 475-8. Date of Electronic Publication: 2015 Sep 22.
DOI: 10.1007/s10517-015-2996-4
Abstrakt: Activity of serum antibodies in vitro binding to endothelial cells in women with normal pregnancy and preeclampsia was studied. Flow cytometry detected peculiarities of antibody binding to endothelial cells in health and disease. Detection of antiendothelial antibodies in trimesters II and III can be diagnostically important in preeclampsia.
Databáze: MEDLINE