| Autor: |
Sousa AS; Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, BR., Lara OA; Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, BR., Papaiordanou F; Instituto de Dermatologia Prof. Rubem David Azulay, Santa Casa da Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, BR., Marchioro GS; Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, BR., Tebcherani AJ; Complexo Hospitalar Padre Bento de Guarulhos, Guarulhos, SP, BR. |
| Abstrakt: |
Severe cutaneous drug reactions include a wide spectrum of clinical manifestations ranging from mild morbilliform cutaneous rash, to severe forms of hypersensitivity. Special attention is given in this report to the acute generalized exanthematous pustulosis (AGEP), induced in 90% of cases by the use of systemic drugs, especially aminopenicillins and macrolides. The incidence of the disease is low, 1-5 cases per million patients / year. The main differential diagnosis is Von Zumbusch's Pustular Psoriasis. The prognosis is generally good and the disease self limited, after withdrawal of the triggering drug. In this report the authors describe a case of AGEP, triggered by ceftriaxone in a patient with psoriasis vulgaris. |
