Ventricular Assist Device in Children with Cardiac Graft Failure.

Autor: Adachi I; From the Congenital Heart Surgery Department, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Guzmán-Pruneda FA, Khan MS, McKenzie ED, Fraser CD Jr
Jazyk: angličtina
Zdroj: ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2015 Nov-Dec; Vol. 61 (6), pp. 729-30.
DOI: 10.1097/MAT.0000000000000281
Abstrakt: We sought to determine whether ventricular assist device (VAD) support is an effective therapy in children with cardiac graft dysfunction. We conducted a retrospective review of VAD usage in this scenario at our institution. Although short-term VAD support was highly successful (89% [eight out of nine] were bridged to recovery), only 29% (2 out of 7) with long-term VAD survived to retransplant. Of note, three out of five mortalities with long-term VAD were related to sepsis (two fungal and one Gram-negative bacterial). Infectious risk imposed by ongoing immunosuppressive therapy limits the role of long-term VAD in this population.
Databáze: MEDLINE