Genome-Wide SNP Analysis of Southern African Populations Provides New Insights into the Dispersal of Bantu-Speaking Groups.

Autor:	González-Santos M; Department of Zoology, University of Oxford, United Kingdom., Montinaro F; Department of Zoology, University of Oxford, United Kingdom Institute of Legal Medicine, Catholic University, Rome, Italy., Oosthuizen O; School of Medicine, University of Namibia, Windhoek, Namibia., Oosthuizen E; School of Medicine, University of Namibia, Windhoek, Namibia., Busby GB; Department of Zoology, University of Oxford, United Kingdom Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom., Anagnostou P; Dipartimento di Biologia Ambientale, Università 'La Sapienza', Rome, Italy Istituto Italiano di Antropologia, Rome, Italy., Destro-Bisol G; Dipartimento di Biologia Ambientale, Università 'La Sapienza', Rome, Italy Istituto Italiano di Antropologia, Rome, Italy., Pascali V; Institute of Legal Medicine, Catholic University, Rome, Italy., Capelli C; Department of Zoology, University of Oxford, United Kingdom cristian.capelli@zoo.ox.ac.uk.
Jazyk:	angličtina
Zdroj:	Genome biology and evolution [Genome Biol Evol] 2015 Sep 11; Vol. 7 (9), pp. 2560-8. Date of Electronic Publication: 2015 Sep 11.
DOI:	10.1093/gbe/evv164
Abstrakt:	The expansion of Bantu-speaking agropastoralist populations had a great impact on the genetic, linguistic, and cultural variation of sub-Saharan Africa. It is generally accepted that Bantu languages originated in an area around the present border between Cameroon and Nigeria approximately 5,000 years ago, from where they spread South and East becoming the largest African linguistic branch. The demic consequences of this event are reflected in the relatively high genetic homogeneity observed across most of sub-Saharan Africa populations. In this work, we explored genome-wide single nucleotide polymorphism data from 28 populations to characterize the genetic components present in sub-Saharan African populations. Combining novel data from four Southern African populations with previously published results, we reject the hypothesis that the "non-Bantu" genetic component reported in South-Eastern Africa (Mozambique) reflects extensive gene flow between incoming agriculturalist and resident hunter-gatherer communities. We alternatively suggest that this novel component is the result of demographic dynamics associated with the Bantu dispersal. (© The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu