Platelet-rich plasma for resistant oral erosions of pemphigus vulgaris: A pilot study.

Autor: EL-Komy MH; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt., Hassan AS; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt., Abdel Raheem HM; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt., Doss SS; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt., EL-Kaliouby M; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt., Saleh NA; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt., Saleh MA; Department of Dermatology, Faculty of Medicine, Cairo University, Egypt.
Jazyk: angličtina
Zdroj: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society [Wound Repair Regen] 2015 Nov-Dec; Vol. 23 (6), pp. 953-5. Date of Electronic Publication: 2015 Nov 04.
DOI: 10.1111/wrr.12363
Abstrakt: Oral erosions and ulcers of pemphigus vulgaris (PV) are a debilitating condition that is usually difficult to treat. The wound healing properties of platelet-rich plasma (PRP) encouraged us to evaluate its usefulness in treatment of non-healing oral PV lesions. Seven patients with chronic oral PV, resistant to conventional therapy, were treated with weekly to monthly injections of PRP of affected mucosal membranes. All recruits reported improvement in pain and mastication and 6 of 7 patients had an improvement in pemphigus disease area index scores with PRP treatment. PRP injections seems to accelerate the healing process and decrease the pain and eating discomfort associated with the oral erosions and ulcers induced by PV.
(© 2015 by the Wound Healing Society.)
Databáze: MEDLINE
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