Evaluation of Simultaneous Transmission of Chikungunya Virus and Dengue Virus Type 2 in Infected Aedes aegypti and Aedes albopictus (Diptera: Culicidae).

Autor:	Nuckols JT; Joint Vaccine Acquisition Program, Medical Countermeasure Systems, United States Army, 1564 Freedman Drive, Fort Detrick, MD 21702., Huang YJ; Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506., Higgs S; Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506., Miller AL; Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0436. Assay Development Services Division, Galveston National Laboratory, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0610., Pyles RB; Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0436. Assay Development Services Division, Galveston National Laboratory, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-0610., Spratt HM; Department of Preventative Medicine and Community Health, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555-1157., Horne KM; Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506., Vanlandingham DL; Biosecurity Research Institute, Kansas State University, 1041 Pat Roberts Hall, Manhattan KS 66506. Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Kansas State University, L-222 Mosier Hall, Manhattan KS 66506. dlvanlan@bri.ksu.edu.
Jazyk:	angličtina
Zdroj:	Journal of medical entomology [J Med Entomol] 2015 May; Vol. 52 (3), pp. 447-51. Date of Electronic Publication: 2015 Mar 15.
DOI:	10.1093/jme/tjv017
Abstrakt:	The simultaneous transmission of chikungunya virus (CHIKV) and dengue viruses (DENV) has been a major public health concern because of their sympatric distribution and shared mosquito vectors. Groups of Aedes aegypti (L.) and Aedes albopictus (Skuse) were orally infected with 1.5 × 10(5) PFU/ml of CHIKV and 3.2 × 10(6) FFU/ml of DENV-2 simultaneously or separately in inverse orders and evaluated for dissemination and transmission by qRT-PCR. Simultaneous dissemination of both viruses was detected for all groups in Ae. aegypti and Ae. albopictus while cotransmission of CHIKV and DENV-2 only occurred at low rates after sequential but not simultaneous infection. (© The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
Databáze:	MEDLINE
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