Syphilis as a Cause of Thoracic Aortic Aneurysm.

Autor: Roberts WC; Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas; Department of Pathology, Baylor University Medical Center, Dallas, Texas; The Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas. Electronic address: wc.roberts@baylorhealth.edu., Barbin CM; Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas., Weissenborn MR; Department of Radiology, Baylor University Medical Center, Dallas, Texas., Ko JM; The Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas., Henry AC; Department of Cardiothoracic Surgery, Baylor University Medical Center, Dallas, Texas.
Jazyk: angličtina
Zdroj: The American journal of cardiology [Am J Cardiol] 2015 Oct 15; Vol. 116 (8), pp. 1298-303. Date of Electronic Publication: 2015 Jul 28.
DOI: 10.1016/j.amjcard.2015.07.030
Abstrakt: In 2009, we described morphologic findings in 22 patients having resection of an ascending aortic aneurysm in the previous 11 years at the Baylor University Medical Center, and histologic examination of the aneurysmal wall disclosed classic findings of syphilitic aortitis. The major purpose of that extensively illustrated report was to describe the characteristic gross features of the aneurysm such that syphilitic aortitis might be better recognized at operation and appropriate antibiotics administered postoperatively. The aim of the present study was to emphasize that syphilis remains a major cause of ascending aortic aneurysm. From January 1, 2009, to December 31, 2014, we studied additional 23 patients who had resection of an ascending aortic aneurysm that again histologically had classic features of syphilitic aortitis. All 23 patients were found to have syphilitic aortitis grossly and histologically. The aneurysm involved the ascending portion of aorta in all 23, the arch portion in 12, and the descending thoracic portion in 10. In conclusion, syphilis has far from disappeared. It remains a major cause of ascending aortic aneurysm.
(Copyright © 2015 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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