[Toxic epidermal necrolysis and development of liver abscesses].

Autor: Domínguez-Borgúa A; Servicio de Medicina Interna, Hospital Regional de Tlalnepantla, ISSEMyM, Edo. de México., González I; Servicio de Medicina Interna, Hospital Regional de Tlalnepantla, ISSEMyM, Edo. de México., Morales L; Servicio de Medicina Interna, Hospital Regional de Tlalnepantla, ISSEMyM, Edo. de México., Martínez-Carrillo FM; Servicio de Medicina Interna, Hospital Regional de Tlalnepantla, ISSEMyM, Edo. de México., Palacios P; Servicio de Medicina Interna, Hospital Regional de Tlalnepantla, ISSEMyM, Edo. de México.
Jazyk: Spanish; Castilian
Zdroj: Gaceta medica de Mexico [Gac Med Mex] 2015 Jul-Aug; Vol. 151 (4), pp. 512-8.
Abstrakt: Pharmacologic hypersensitivities commonly express cutaneous manifestations, and the highest mortality is found in Stevens Johnson's syndrome and toxic epidermal necrolysis, mostly associated with antibiotics and anticonvulsive drugs. Toxic epidermal necrolysis is related in 80% of cases to pharmacologic hypersensitivity and systemic consequences may be found; hepatic injury has been described, but the finding of liver abscesses has not been reported among common injuries. The case of a patient with a rapid development of multiple liver abscesses in the clinical setting of hypersensitivity due to lamotrigine and the discussion of probable etiologies and management is presented.
Databáze: MEDLINE