A MLC-based inversely optimized 3D spatially fractionated grid radiotherapy technique.

Autor: Jin JY; Radiation Oncology, Georgia Regents University, Augusta, United States. Electronic address: jjin@gru.edu., Zhao B; Radiation Oncology, Henry Ford Hospital, Detroit, United States., Kaminski JM; Radiation Oncology, Georgia Regents University, Augusta, United States., Wen N; Radiation Oncology, Henry Ford Hospital, Detroit, United States., Huang Y; Radiation Oncology, Henry Ford Hospital, Detroit, United States., Vender J; Neurosurgery, Georgia Regents University, Augusta, United States., Chetty IJ; Radiation Oncology, Henry Ford Hospital, Detroit, United States., Kong FM; Radiation Oncology, Georgia Regents University, Augusta, United States.
Jazyk: angličtina
Zdroj: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2015 Dec; Vol. 117 (3), pp. 483-6. Date of Electronic Publication: 2015 Aug 12.
DOI: 10.1016/j.radonc.2015.07.047
Abstrakt: This study presents a MLC-based, 3D grid-therapy technique with characteristics of both 3D-conformal-radiotherapy and grid-therapy. It generates a brachytherapy-like dose distribution, with D50% of 20, 9.8, 5.4 and 2.9-Gy, for the spheres, target, 1 cm-outershell and 2 cm-outershell, respectively. It may provide a strategy to deliver ablative doses to large tumors safely.
(Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.)
Databáze: MEDLINE
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