Oropharyngeal perinatal colonization by human papillomavirus.

Autor: Sánchez-Torices MS; Servicio de Otorrinolaringología, Complejo Hospitalario de Jaén, Jaén, España. Electronic address: marisolsancheztorices@gmail.com., Corrales-Millan R; Servicio de Otorrinolaringología, Complejo Hospitalario de Jaén, Jaén, España., Hijona-Elosegui JJ; Servicio de Ginecología y Obstetricia, Complejo Hospitalario de Jaén, Jaén, España.
Jazyk: English; Spanish; Castilian
Zdroj: Acta otorrinolaringologica espanola [Acta Otorrinolaringol Esp] 2016 May-Jun; Vol. 67 (3), pp. 135-41. Date of Electronic Publication: 2015 Aug 12.
DOI: 10.1016/j.otorri.2015.05.002
Abstrakt: Introduction and Objective: Human papillomavirus (HPV) infection is the most common human sexually transmitted disease. It is clinically relevant because this condition is necessary for the development of epithelial cervical cancer, and it is also a factor closely associated with the occurrence of diverse tumours and various benign and malignant lesions of the head and neck area. The infective mechanism in most of these cases is associated with sexual intercourse, but there is recent scientific evidence suggesting that HPV infection may also be acquired by other routes of infection not necessarily linked to sexual contact. One of them is vertical transmission from mother to child, either during pregnancy or at the time of delivery. The aim of our research was to study maternal-foetal HPV transmission during childbirth in detail, establishing the rate of oropharyngeal neonatal HPV in vaginal deliveries.
Method: The presence and type of HPV viral DNA at the time of delivery in samples of maternal cervical secretions, amniotic fluid, venous cord blood samples and neonatal oropharynx in pregnant women (and their babies) were determined.
Results: The rate of oropharyngeal neonatal HPV colonization in vaginal deliveries was 58.24%.
Conclusions: The maternal and neonatal HPV colonization mechanism is essentially, but not exclusively, transvaginal.
(Copyright © 2014 Elsevier España, S.L.U. y Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.)
Databáze: MEDLINE