THE ACTION OF AVOCADO OIL ON THE LIPIDOGRAM OF WISTAR RATS SUBMITTED TO PROLONGED ANDROGENIC STIMULUM.
| Autor: | de Souza Abboud R; Department of Morphology, Laboratory of Cellular and Extracellular Biomorphology Biomedic Institute, Federal Fluminense University.. chagas.m@gmail.com., Alves Pereira V; Department of Morphology, Laboratory of Cellular and Extracellular Biomorphology Biomedic Institute, Federal Fluminense University.. chagas.m@gmail.com., Soares da Costa CA; Laboratory of Experimental Nutrition. Departament of Nutrition and Dietetics. Fluminense Federal University. Rio de Janeiro, Brazil.. chagas.m@gmail.com., Teles Boaventura G; Laboratory of Experimental Nutrition. Departament of Nutrition and Dietetics. Fluminense Federal University. Rio de Janeiro, Brazil.. chagas.m@gmail.com., Alves Chagas M; Department of Morphology, Laboratory of Cellular and Extracellular Biomorphology Biomedic Institute, Federal Fluminense University.. chagas.m@gmail.com. |
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| Jazyk: | angličtina |
| Zdroj: | Nutricion hospitalaria [Nutr Hosp] 2015 Aug 01; Vol. 32 (2), pp. 696-701. Date of Electronic Publication: 2015 Aug 01. |
| DOI: | 10.3305/nh.2015.32.2.9009 |
| Abstrakt: | Introduction: the abuse of steroid hormones administered in chronic form may cause alterations in the lypidic profile, conveying na increase in the levels of LDL, and reduction in the levels of HDL. In average, 53.44% of the lypidic composition of the avocado core is composed of oleic acid (which is a phytosterol) and the study of the hypolipemiating effect of these substances has been performed aiming at the prevention and control of dislypidemias. Objective: to assess the potential hypolipemiant power of the avocado oil on the lypidogram of adult male Wistar rats submitted to prolonged androgenic hiperestimulation. Materials and Methods: twenty eight Wistar rats were divided in 4 groups of 7 animals: the control group (CG); Avocado Oil Group (AOG) fed with a staple based on Avocado Oil; Induced Grupo (IG); and the Induced Grupo fed with a staple based on Avocado Oil (AOIG). The inducing was performed through surgery to subcutaneously implant sillicon pellets suffed with 1 ml of testosterone propionate which were replaced at every 4 weeks. Results: VLDL (AOIG: 28.14 ± 4.45; IG:36.83 ± 5.56 mg/ml); Triglicerides (AOIG: 140.07 ± 22.66; IG: 187.2 ± 27 mg/ml); HDL (AOIG: 40, 67 ± 1.2; GI: 35.09 ± 0.8; AOG: 32.31 ± 2.61 e CG: 32.36 ± 4.93 mg/ml) Testosterone (AOIG:1.42 ± 0.46; GI: 2.14 ± 0.88; AOG: 2.97 ± 1.34 e CG:1.86 ± 0.79 ng/ml). Conclusion: avocado Oil exerted a direct regulating effect on the lypidic profile, acting efficiently on animals submmited to androgenic stimulation through a prolonged period. (Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.) |
| Databáze: | MEDLINE |
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