Recent advances in topical formulation carriers of antifungal agents.

Autor: Bseiso EA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, October 6 University, Giza, Egypt., Nasr M, Sammour O, Abd El Gawad NA
Jazyk: angličtina
Zdroj: Indian journal of dermatology, venereology and leprology [Indian J Dermatol Venereol Leprol] 2015 Sep-Oct; Vol. 81 (5), pp. 457-63.
DOI: 10.4103/0378-6323.162328
Abstrakt: Fungal infections are amongst the most commonly encountered diseases affecting the skin. Treatment approaches include both topical and oral antifungal agents. The topical route is generally preferred due to the possible side effects of oral medication. Advances in the field of formulation may soon render outdated conventional products such as creams, ointments and gels. Several carrier systems loaded with antifungal drugs have demonstrated promising results in the treatment of skin fungal infections. Examples of these newer carriers include micelles, lipidic systems such as solid lipid nanoparticles and nanostructured lipid carriers, microemulsions and vesicular systems such as liposomes, niosomes, transfersomes, ethosomes, and penetration enhancer vesicles.
Databáze: MEDLINE