| Autor: |
Romano TG; Nephrology Department, ABC Medical School, Hospital Sirio Libanes, Brazil., Vieira Junior JM; Intensive Care Unit, Hospital Sirio Libanes, Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of clinical medicine research [J Clin Med Res] 2015 Sep; Vol. 7 (9), pp. 667-71. Date of Electronic Publication: 2015 Jul 24. |
| DOI: |
10.14740/jocmr2261w |
| Abstrakt: |
Acute kidney injury (AKI) is a major complication in patients with acute liver failure and chronic liver disease. Hemodynamic changes appear to be the principal alterations in these conditions, therefore there should be no known structural abnormalities responsible for AKI. On the other hand, several authors have published data on structural changes known as bile cast nephropathy or cholemic nephrosis, which basically consist of the presence of bile casts in tubular lumen analogous to those observed in myeloma. Although these findings are well documented, there is a lack of reproducibility by other authors. This paper aims to discuss, through evidence-based medical literature, the role of biliary salts on kidney injury development. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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