Importance of molecular typing in confirmation of the source of a national hepatitis A virus outbreak in Norway and the detection of a related cluster in Germany.

Autor: Guzman-Herrador BR; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway. BernardoRafael.Guzman.Herrador@fhi.no., Panning M; Institute of Virology, University Medical Centre, Freiburg, Germany., Stene-Johansen K; Department of Virology, Norwegian Institute of Public Health, Oslo, Norway., Borgen K; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway., Einöder-Moreno M; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway.; European Program for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Huzly D; Institute of Virology, University Medical Centre, Freiburg, Germany., Jensvoll L; Norwegian Food Safety Authority, Head Office, Ås, Norway., Lange H; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway.; European Program for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden., Maassen S; Public Health Office, Freiburg, Germany., Myking S; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway.; Department of Virology, Norwegian Institute of Public Health, Oslo, Norway., Myrmel M; Norwegian University of Life Sciences, Oslo, Norway., Neumann-Haefelin C; Department of Medicine II, University Medical Centre, Freiburg, Germany., Nygård K; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway., Wenzel JJ; Institute of Clinical Microbiology and Hygiene, Regensburg University Medical Centre, Regensburg, Germany., Øye AK; Norwegian University of Life Sciences, Oslo, Norway., Vold L; Department of Infectious Disease Epidemiology, Norwegian Institute of Public Health, Postboks 4404 Nydalen, NO-0403, Oslo, Norway.
Jazyk: angličtina
Zdroj: Archives of virology [Arch Virol] 2015 Nov; Vol. 160 (11), pp. 2823-6. Date of Electronic Publication: 2015 Aug 07.
DOI: 10.1007/s00705-015-2531-y
Abstrakt: In March 2014, after an increase of notifications of domestically acquired hepatitis A virus infections, an outbreak investigation was launched in Norway. Sequenced-based typing results showed that these cases were associated with a strain that was identical to one causing an ongoing multinational outbreak in Europe linked to frozen mixed berries. Thirty-three confirmed cases with the outbreak strain were notified in Norway from November 2013 to June 2014. Epidemiological evidence and trace-back investigations linked the outbreak to the consumption of a berry mix cake. Identification of the hepatitis A virus outbreak strain in berries from one of the implicated cakes confirmed the cake to be the source. Subsequently, a cluster in Germany linked to the cake was also identified.
Databáze: MEDLINE