[Intra cranial meningiomas and long term use of cyproterone acetate with a conventional dose in women. A report of two cases of tumor decrease after treatment withdrawal].

Autor: Botella C; Service de neurochirurgie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France. Electronic address: celine-bc@hotmail.fr., Coll G; Service de neurochirurgie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France., Lemaire JJ; EA 7282 IGCNC (Image-Guided Clinical Neuroscience and Connectomics) Clermont université, université d'Auvergne, UFR Médecine, 63000 Clermont-Ferrand, France; Service de neurochirurgie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France., Irthum B; EA 7282 IGCNC (Image-Guided Clinical Neuroscience and Connectomics) Clermont université, université d'Auvergne, UFR Médecine, 63000 Clermont-Ferrand, France; Service de neurochirurgie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand, France.
Jazyk: francouzština
Zdroj: Neuro-Chirurgie [Neurochirurgie] 2015 Oct; Vol. 61 (5), pp. 339-42. Date of Electronic Publication: 2015 Aug 04.
DOI: 10.1016/j.neuchi.2015.05.002
Abstrakt: The action of synthetic progestogens, prescribed at a conventional dose in women, for a meningioma, is still poorly understood, and could be related to progesterone receptors. We report two cases illustrating multiple meningiomas with stabilization or tumor reduction after withdrawal of cyproterone acetate originally prescribed for a long term period. We also review the influence of synthetic progestogens on meningiomas, particularly the impact of treatment withdrawal.
(Copyright © 2015 Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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