Buccal Versus Lingual Mucosa Graft in Anterior Urethroplasty: A Prospective Comparison of Surgical Outcome and Donor Site Morbidity.

Autor: Lumen N; Department of Urology, Ghent University Hospital, Ghent, Belgium., Vierstraete-Verlinde S; Department of Urology, Ghent University Hospital, Ghent, Belgium., Oosterlinck W; Department of Urology, Ghent University Hospital, Ghent, Belgium., Hoebeke P; Department of Urology, Ghent University Hospital, Ghent, Belgium., Palminteri E; Center for Urethral and Genitalia Reconstructive Surgery, Arezzo, Italy., Goes C; Department of Urology, Ghent University Hospital, Ghent, Belgium., Maes H; Department of Urology, Ghent University Hospital, Ghent, Belgium. Electronic address: poli.urologie@uzgent.be., Spinoit AF; Department of Urology, Ghent University Hospital, Ghent, Belgium.
Jazyk: angličtina
Zdroj: The Journal of urology [J Urol] 2016 Jan; Vol. 195 (1), pp. 112-7. Date of Electronic Publication: 2015 Aug 01.
DOI: 10.1016/j.juro.2015.07.098
Abstrakt: Purpose: We prospectively compared buccal mucosa graft and lingual mucosa graft urethroplasty with respect to donor site morbidity and urethroplasty outcome.
Materials and Methods: Patients treated with buccal mucosa graft (29) or lingual mucosa graft (29) urethroplasty were included in the study. Oral pain and morbidity were assessed using the numeric rating scale (scale 0 to 10) as well as an in-home questionnaire administered 3 days, 2 weeks and 6 months postoperatively.
Results: After a mean (± SD) followup of 30 (± 13) months successful urethroplasty was achieved in 24 (82.8%) and 26 (89.7%) patients treated with buccal mucosa graft and lingual mucosa graft, respectively (p = 0.306). Median numeric rating scale after 3 days, 2 weeks and 6 months was 4, 2 and 0 for buccal mucosa graft and 6, 3 and 0 for lingual mucosa graft, respectively, with no statistical differences between the groups. At day 3 significantly more patients in the lingual mucosa graft group had severe difficulties with eating and drinking (62.1% vs 24.1%, p = 0.004) and speaking (93.1% vs 55.2%, p = 0.001), and had dysgeusia (48.3% vs 13.8%, p = 0.01). Two weeks postoperatively speech impairment was still more frequent with lingual mucosa graft (55.2% vs 13.8%, p = 0.002), whereas oral tightness was more frequent with buccal mucosa graft (41.4% vs 6.9%, p = 0.005). After 6 months 44.8% and 31% of patients treated with buccal mucosa graft and lingual mucosa graft, respectively, still reported sensitivity disorders (p = 0.279).
Conclusions: The success of urethroplasty with lingual and buccal mucosa grafts was similar. Oral pain was not different after both grafts. In the early postoperative period there were differences in oral morbidity between buccal and lingual mucosa grafts. Long-term oral morbidity was not infrequent with both grafts.
(Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE