| Autor: |
Popova VV; A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119992, Russia., Dunaevsky YE, Domash VI, Semenova TA, Beliakova GA, Belozersky MA |
| Jazyk: |
angličtina |
| Zdroj: |
Archives of microbiology [Arch Microbiol] 2015 Oct; Vol. 197 (8), pp. 1001-10. Date of Electronic Publication: 2015 Jul 26. |
| DOI: |
10.1007/s00203-015-1132-1 |
| Abstrakt: |
The activities of secreted and mycelial inhibitors of proteolytic enzymes from fungi of the order Hypocreales have been investigated. Inhibitors of bromelain, papain, and trypsin of low molecular mass (about 1 kDa) and a subtilisin proteinaceous inhibitor with molecular mass of 45 kDa were revealed in the culture liquid of the fungus Tolypocladium cylindrosporum. The subtilisin inhibitor from T. cylindrosporum has antibiotic properties, significantly decreased the activity of purified bacterial enzymes, and prevented the growth of the bacterium Pseudomonas sp. Data suggesting the existence in fungi of the Hypocreales order of two pools of peptidase inhibitors have been obtained. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
Full text from SpringerLink