Unusual skin manifestation of hand, foot and mouth disease associated with coxsackievirus A6: cases report.

Autor: Chatproedprai S; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330 Thailand., Tempark T; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330 Thailand., Wanlapakorn N; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330 Thailand., Puenpa J; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330 Thailand., Wananukul S; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330 Thailand., Poovorawan Y; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330 Thailand.
Jazyk: angličtina
Zdroj: SpringerPlus [Springerplus] 2015 Jul 17; Vol. 4, pp. 362. Date of Electronic Publication: 2015 Jul 17 (Print Publication: 2015).
DOI: 10.1186/s40064-015-1143-z
Abstrakt: Background: Hand, food, and mouth disease (HFMD) is a highly contagious disease caused by enteroviruses infection. It is a health problem in young children under 5 years of age worldwide. The common causative agents are coxsackievirus A 16 (CA16) and enterovirus 71 (EV71). In recent years, coxsackievirus A6 (CA6) has emerged to be one of the major etiologic agents of HFMD worldwide including in Thailand.
Case Description: We reported cases with unusual skin manifestations of CA6-associated HFMD such as widespread severe cutaneous eruption, large vesicles (varicelliform), purpuric-like lesions or Gianotti-Crosti like eruptions.
Discussion and Evaluation: Molecular characterization of the CA6 strains from those patients found that all were clustered in the same group of CA6 that are currently circulating in Thailand.
Conclusions: Clinicians need to be aware of the expanded range of cutaneous findings in CA6-associated HFMD in order to properly consider the diagnosis, management and prevention.
Databáze: MEDLINE
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