Primary small bowel melanoma. A case report and a review of the literature.

Autor: Spiridakis KG, Polichronaki EE, Sfakianakis EE, Flamourakis ME, Margetousakis TH, Xekalou AS, Lianeris GK, Giannikaki ES, Christodoulakis MS
Jazyk: angličtina
Zdroj: Il Giornale di chirurgia [G Chir] 2015 May-Jun; Vol. 36 (3), pp. 128-32.
Abstrakt: Primary malignant melanoma originating from the small intestine is extremely rare. Only a limited number of cases are described in the literature. Most commonly small intestine is affected by metastatic tumors from other primary lesions. We present a case of a 68-years old male diagnosed with primary malignant melanoma as an ulcerated and bleeding mass in the jejunum--located 40 cm away from the Treitz band. In our case the diagnosis was confirmed at laparotomy and enterectomy. Histology revealed a neoplastic infiltration involving the entire intestinal mucosa, with atypia of neoplastic cells and immunoreactivity to HMB45(+), Melan A(+) and S100(+), confirming the diagnosis of melanoma. There was not revealed a primary lesion in the skin, eye, anus, rectum or in other location by the post-operative investigation. An eleven-month close follow-up has not revealed any metastasis. Therefore a definitive diagnosis of primary malignant melanoma was set.
Databáze: MEDLINE