The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent Males.

Autor:	McGlade E; 1 University of Utah, Salt Lake City, UT, USA., Agoston AM; 1 University of Utah, Salt Lake City, UT, USA., DiMuzio J; 1 University of Utah, Salt Lake City, UT, USA., Kizaki M; 2 KYOWA HAKKO BIO CO., LTD, Tsukuba, Ibaraki, Japan., Nakazaki E; 2 KYOWA HAKKO BIO CO., LTD, Tsukuba, Ibaraki, Japan., Kamiya T; 3 KYOWA HAKKO U.S.A., INC., New York, NY, USA., Yurgelun-Todd D; 1 University of Utah, Salt Lake City, UT, USA.
Jazyk:	angličtina
Zdroj:	Journal of attention disorders [J Atten Disord] 2019 Jan; Vol. 23 (2), pp. 121-134. Date of Electronic Publication: 2015 Jul 15.
DOI:	10.1177/1087054715593633
Abstrakt:	Objective: This study assessed the effects of citicoline, a nutraceutical, on attention, psychomotor function, and impulsivity in healthy adolescent males. Method: Seventy-five healthy adolescent males were randomly assigned to either the citicoline group ( n = 51 with 250 or 500 mg citicoline) or placebo ( n = 24). Participants completed the Ruff 2&7 Selective Attention Test, Finger Tap Test, and the Computerized Performance Test, Second Edition (CPT-II) at baseline and after 28 days of supplementation. Results: Individuals receiving citicoline exhibited improved attention ( p = 0.02) and increased psychomotor speed ( p = 0.03) compared with those receiving placebo. Higher weight-adjusted dose significantly predicted increased accuracy on an attention task ( p = 0.01), improved signal detectability on a computerized attention task ( p = 0.03), and decreased impulsivity ( p = 0.01). Discussion: Adolescent males receiving 28 days of Cognizin® citicoline showed improved attention and psychomotor speed and reduced impulsivity compared to adolescent males who received placebo.
Databáze:	MEDLINE
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