Ethylene oxide doses in ethene-exposed fruit store workers.

Autor: Törnqvist MA; Department of Radiobiology, University of Stockholm, Sweden., Almberg JG, Bergmark EN, Nilsson S, Osterman-Golkar SM
Jazyk: angličtina
Zdroj: Scandinavian journal of work, environment & health [Scand J Work Environ Health] 1989 Dec; Vol. 15 (6), pp. 436-8.
DOI: 10.5271/sjweh.1829
Abstrakt: Blood samples from 10 ethene-exposed fruit store workers and 10 referents were analyzed for the level of hydroxyethyl adducts to N-terminal valine in hemoglobin (Hb). A statistically significant difference was obtained between the nonsmoking workers (N = 7) and the nonsmoking referents (N = 6). This finding demonstrates that ethene is metabolized to ethylene oxide in man. According to this preliminary study, ethene exposure at 0.3 (uncertainty range 0.1-1) ppm during work hours increases the adduct level by 23 pmol/g Hb. This figure is compatible with a metabolic conversion of 3% (1-10%) of the inhaled ethene to ethylene oxide.
Databáze: MEDLINE