Cancer in inflammatory bowel disease.

Autor: Gyde SN; North Birmingham Health Authority, Good Hope Hospital, Birmingham, U.K.
Jazyk: angličtina
Zdroj: Scandinavian journal of gastroenterology. Supplement [Scand J Gastroenterol Suppl] 1989; Vol. 170, pp. 79-80; discussion 79-80.
DOI: 10.3109/00365528909091360
Abstrakt: There is convincing evidence that patients with ulcerative colitis carry a higher risk of developing colorectal cancer than the general population. This risk is as high as 19-fold that in the general population. The results of the Birmingham study (Gut 1988, 29, 206-217) suggest that extensive colitis patients have a genetic predisposition for colorectal cancer and that long-standing inflammation is not of primary importance in the initiation/promotion of cancer in this disease. Population-based studies, although difficult to carry out, should be the epidemiologic method of choice for determining the risk of cancer in future studies.
Databáze: MEDLINE