Autor: |
Pham NT; Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine., Thongprachum A, Tran DN, Nishimura S, Shimizu-Onda Y, Trinh QD, Khamrin P, Ukarapol N, Kongsricharoern T, Komine-Aizawa S, Okitsu S, Maneekarn N, Hayakawa S, Ushijima H |
Jazyk: |
angličtina |
Zdroj: |
Japanese journal of infectious diseases [Jpn J Infect Dis] 2016; Vol. 69 (1), pp. 77-9. Date of Electronic Publication: 2015 Jul 10. |
DOI: |
10.7883/yoken.JJID.2014.582 |
Abstrakt: |
A total of 29 Campylobacter jejuni and C. coli strains were isolated from Thai and Japanese children with diarrhea using the Loop-mediated Isothermal Amplification method. The samples were evaluated for mutations in gyrA and 23S rRNA in order to assess resistance against fluoroquinolones and macrolides, respectively. Among the isolated strains, 9 (8 C. jejuni and 1 C. coli) were from Thai children, and the other 20 (C. jejuni) were isolated from Japanese children. High fluoroquinolone resistance rates were observed in Thai (66.7%) and Japanese (90%) children. Macrolide resistance was not observed in Japanese children but was observed at a considerable rate of 12.5% of C. jejuni isolated in the Thai cohort. The results indicate that continuous monitoring of resistance of Campylobacter strains to fluoroquinolones and macrolides is definitely necessary. |
Databáze: |
MEDLINE |
Externí odkaz: |
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